Description
SuLT2A1, also known dehydroepiandrosterone sulphotransferase, belongs to the sulfotransferase family. This protein is mainly expressed in liver and adrenal tissues, and to a lesser extent in kidney. It catalyzes the 3'-phosphoadenosine 5'-phosphosulfate-dependent sulfation of a wide variety of steroids in human liver and adrenal tissues, and is also responsible for most of the sulfation of bile acids in human liver. Recombinant human SuLT2A1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography